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New findings expand genetic knowledge of autism underpinnings

 

Hundreds of novel genetic variants across an ancestrally diverse cohort of 195 families, including 222 people with autism spectrum disorder (ASD), have been identified by researchers at UT Southwestern Medical Center, expanding the catalog of known mutations associated with ASD.

Program enhances stroke care at nearly 3,000 U.S. hospitals

 

A study led by a researcher at UT Southwestern Medical Center shows a national initiative significantly improved stroke outcomes for millions of patients over its first 20 years, enhancing quality of care and consistency at more than 2,800 U.S. hospitals including UTSW.

Combination therapy slows cognitive decline, research shows

 

A novel combination therapy slowed cognitive decline in elderly patients with a history of depression – a major risk factor for developing Alzheimer’s and other forms of dementia, a study led by UT Southwestern Medical Center’s new Chair and Professor of Psychiatry found.

UTSW study explores link between high school IQ and alcohol use

 

A person’s IQ during high school is predictive of alcohol consumption later in life, according to a study by UT Southwestern Medical Center researchers published in Alcohol and Alcoholism.

UTSW Research: Alcohol-associated liver disease, depression treatment, and more

 

Researchers have long known that outcomes for alcohol-associated liver disease (ALD) aren’t equal among all races and ethnicities in the U.S., but differences among these groups have been less clear.

UTSW study reveals how key protein affects neuron structure

 

A protein called torsinA plays a key role in the early development of neurons, determining where nuclear pores are placed in the membrane that encloses the nucleus of nerve cells, a study led by UT Southwestern Medical Center researchers shows.

Natural grass may pose greater risk for football concussions

 

Young football players who sustained a head-to-ground concussion practicing or playing games on natural grass experienced more symptoms – and significantly higher severity – than those who suffered concussions on artificial turf, researchers at UT Southwestern Medical Center found.

Study identifies weight-loss drug target in the brain

 

A team led by researchers from UT Southwestern Medical Center and a university in South Korea has identified a subset of brain cells whose activation may be partially responsible for the effects of a popular class of weight loss drugs that includes semaglutide and tirzepatide.

Electroconvulsive therapy or ketamine? Clinical factors affect outcomes

 

Patients with moderate to severe treatment-resistant depression (TRD) might have better symptom relief from ketamine infusions than from electroconvulsive therapy (ECT), but those with severe TRD could benefit more from ECT early in treatment, an analysis led by a UT Southwestern Medical Center researcher shows.

Diagnosing essential tremor after death helps families learn risk

 

A statistical tool designed to analyze 11 characteristics of postmortem brains reliably diagnosed a common neurodegenerative disease known as essential tremor (ET), a study led by researchers at UT Southwestern Medical Center and Columbia University shows.