Tau Protein

Marc Diamond, M.D., studies how this protein changes its shape to transition from a healthy form to one that causes disease. Additionally, his work elucidates how distinct pathological forms of tau lead to different diseases.

Lukasz Joachimiak, Ph.D. uses advanced biochemical tools coupled with mass spectrometry to reveal how proteins fold in specific regions and interact with each other. This work has revealed novel conformations of the tau protein that are associated with disease.